Mini workshop: Genome exploration

University of Copenhagen, at 13:00, LIFE, Room 3-14 at Thorvaldsensvej 40, Frederiksberg

Registration is not necessary. Refreshments will be served.


13:00-13:05 Welcome
Jan Gorodkin, University of Copenhagen.

13:05-13:50 Avalanche probing in High-throughput sequencing data
Steve  Hofmann,  LIFE  Research  Center  and  Interdisciplinary  Center  for
Bioinformatics, University of Leipzig.

High-throughput sequencing (HTS) analysis for the first time offers to possibility to quickly investigate whole genomes and transcriptomes in an essentially unbiased way. However, on the other side of the  sequencer, scientists are flooded with terabytes of sequence data rising the need for efficient and fast ways to analyze it. Here, some  interesting  examples of HTS-data and strategies for analysis will be reviewed. A special focus will be on mapping, splice-site detection and transcription start site prediction.

13:50-14:10 Break

14:10-14:55 How to assess (non)coding potential?
Sven Findeiss, Department of Computer Science and  Interdisciplinary  Center for Bioinformatics, University of Leipzig

Independent of species and sequences which are analyzed, researchers working in comparative genomics always have to face the same old question: Does my new sequence have any function? In fact, the assessment of potentially coding and noncoding regions still is a pressing practical problem. Therefore, two in silico methods and their broad field of application are presented.