CRS M1252265

[UCSC Genome browser]   [CRS region C5836030]   [Open all submenus]   [Close all submenus]

+ Summary

Location human (hg38)PscoreFDR
chrX:15599127-15599177 (forward)54.6216.70 %

[Covariance model (INFERNAL 1.1.1)]


100 species tree

Sequence identityNumber speciesG+C contentAlignment lengthLog Odds SI stem / loop
60.42 %2527.78 %1120.25
EnergyCompensatory
base pair changes
Mutual informationStructure conservation
SCI
Structure conservation
SECI
-4.77 kcal/mol80.200.870.67

17 species tree

Sequence identityNumber speciesAlignment lengthStructure conservation
SCI
Re-alignment
72.05 %6580.0020.82 %

+ Consensus structure

100 species tree

Structure as dot-bracket notation:
((((..............................(((........(((((((...................................)))))))..)...))......))))
Structure as forna illustration (bases are named as consensus sequence and colored by relative entropy):
Color scheme relative entropy

17 species tree

Structure with human sequence and color coding of conservation: [PNG]

+ Alignment

100 species tree

[PNG]  [STOCKHOLM 1.0]


17 species tree

[PNG]  [STOCKHOLM 1.0]

[View 17 species tree alignment]

+ Overlap with RNAcentral

CRS M1252265 is not included in RNAcentral.

+ Annotation

StrandGenomic contextGene identifierDistance (0 if overlap)
ForwardIntergenicantisense|ENSG00000225833|GS1-594A7.33704
ReverseMRNA_Intronmrna_intron|ENSG00000130234|ACE20
BiotypeRfamPhyloCSF
intronicNULLNULL
Repeat MaskerTandem Repeats
NULLNULL
CpG islandExon-Intron Junction
NULL1
Common SNP
(dbSNP 147)
Flagged SNP
(dbSNP 147)
NULLNULL
Disease association from GWAS
NULL

+ Evolutionary selection

+ Covarying base pairs

100 species tree

Consensus structure with covarying base pairs (estimated by R-scape with E-value<0.05) highlighted in green (R2R drawing): [PDF]

Number base pairs (bps)Expected covarying bpsObserved covarying bps
140.3 +/- 0.60

+ Chromatin signatures

DNase hypersensitive sites (95 cell types from ENCODE)scorecell types
NULLNULL
Genome Segmentations from ENCODEGM12878H1hESCHeLaS3HepG2HUVECK562
RRNULLRRR

+ Protein binding sites

+ Expression

Poly-A selected RNA (Human Body Map 2.0)Total RNA (Human ENCODE phase 3)
TissueExpression level (CPM/RLE)TissueExpression level (CPM/RLE)
Adipose0Skin of body0
Colon0Stomach0
Heart0.345421Heart0.876372
Liver0Liver0
Lung0Lung0
Ovary0Uterus0.235531
Prostate0Urinary bladder0
Muscle0Skeletal muscle0
Thyroid0Thyroid gland0
Brain0Frontal cortex0
Lymph0Temporal lobe0
Testes0Cerebellum0
Blood0Spinal cord0
Kidney0Diencephalon0
Breast0Parietal lobe0
Adrenalin0Occipital0
Metanephros0
Tongue0
Camera type eye0

Targeted CRS expression in human fetal brain (CaptureSeq)
Read island identifierHybridization temperatureStrandP-valueMax. Read Count
NULLNULLNULLNULLNULL

+ Transcript boundaries and stability