CRS M2544006

100 species tree

Structure as dot-bracket notation:

((((....(((((...........((((.(((..((((................))))..)))..))))......))).)).....))))

Structure as forna illustration (bases are named as consensus sequence and colored by relative entropy):

17 species tree

Structure with human sequence and color coding of conservation: [PNG]

100 species tree

[PNG]  [STOCKHOLM 1.0]

17 species tree

[PNG]  [STOCKHOLM 1.0]

[View 17 species tree alignment]

Strand	Genomic context	Gene identifier	Distance (0 if overlap)
Forward	Intergenic	exon|ENSG00000102010|BMX	-16214
Reverse	MRNA_Intron	mrna_intron|ENSG00000130234|ACE2	0

Biotype	Rfam	PhyloCSF
intronic	NULL	NULL

Repeat Masker	Tandem Repeats
NULL	NULL

CpG island	Exon-Intron Junction
NULL	1

Common SNP (dbSNP 147)	Flagged SNP (dbSNP 147)
NULL	NULL

Disease association from GWAS
NULL

Selection ratio (SR) (FDR(SR))	PhastCons score	Minor Allele Frequency (p-value)
NA	0.0040	NA

100 species tree

Consensus structure with covarying base pairs (estimated by R-scape with E-value<0.05) highlighted in green (R2R drawing): [PDF]

Number base pairs (bps)	Expected covarying bps	Observed covarying bps
20	0.7 +/- 0.8	1

Significant covarying base pairs (E-value<0.05)

Left pos	Right pos	Score	E-value	Substitutions	Power
30	63	24.21	3.9508e-2	11	0.09

DNase hypersensitive sites (95 cell types from ENCODE)	score	cell types
	NULL	NULL

Genome Segmentations from ENCODE	GM12878	H1hESC	HeLaS3	HepG2	HUVEC	K562
	R	R	R	R	R	R

Transcription factor (ChIP)
NULL

RNA binding protein (CLIP)	P-value
NULL

Poly-A selected RNA (Human Body Map 2.0)		Total RNA (Human ENCODE phase 3)
Tissue	Expression level (CPM/RLE)	Tissue	Expression level (CPM/RLE)
Adipose	0	Skin of body	0
Colon	0	Stomach	0
Heart	0	Heart	1.12453
Liver	0	Liver	0
Lung	0	Lung	0
Ovary	0	Uterus	0.235531
Prostate	0	Urinary bladder	0
Muscle	0	Skeletal muscle	0
Thyroid	0	Thyroid gland	0
Brain	0	Frontal cortex	0.0816212
Lymph	0	Temporal lobe	0.0833107
Testes	0	Cerebellum	0
Blood	0	Spinal cord	0
Kidney	0	Diencephalon	0.0939208
Breast	0	Parietal lobe	0
Adrenalin	0	Occipital	0.0478313
		Metanephros	0
		Tongue	0
		Camera type eye	0.0793836

Targeted CRS expression in human fetal brain (CaptureSeq)
Read island identifier	Hybridization temperature	Strand	P-value	Max. Read Count
NULL	NULL	NULL	NULL	NULL

Closest upstream 5' site (CAGE signal)
Distance	Strand	Maximal expression	Aggregated sum of expression	Cell type-specific score
28132	-	175.5710	652.0250	0.7371

Closest downstream poly-A site (3'-end sequencing)
Distance	Strand	Number of libraries
8712	-	2

Transcript stability (CAGE signal)
Distance	Strand	Expression in control cells	Expression after exosom depletion	Exosome sensitivity
81042	-	1.4375	3.0818	0.5336