CRS M2544015

100 species tree

Structure as dot-bracket notation:

(((((((..................(((..(((((.....)))))..)))((((.......))))..........................)))))))

Structure as forna illustration (bases are named as consensus sequence and colored by relative entropy):

17 species tree

Structure with human sequence and color coding of conservation: [PNG]

100 species tree

[PNG]  [STOCKHOLM 1.0]

17 species tree

[PNG]  [STOCKHOLM 1.0]

[View 17 species tree alignment]

Strand	Genomic context	Gene identifier	Distance (0 if overlap)
Forward	Intergenic	antisense|ENSG00000225833|GS1-594A7.3	581
Reverse	Intergenic	exon|ENSG00000130234|ACE2	136

Biotype	Rfam	PhyloCSF
intergenic	NULL	NULL

Repeat Masker	Tandem Repeats
NULL	NULL

CpG island	Exon-Intron Junction
NULL	1

Common SNP (dbSNP 147)	Flagged SNP (dbSNP 147)
NULL	NULL

Disease association from GWAS
NULL

Selection ratio (SR) (FDR(SR))	PhastCons score	Minor Allele Frequency (p-value)
NA	0.8248	NA

100 species tree

Consensus structure with covarying base pairs (estimated by R-scape with E-value<0.05) highlighted in green (R2R drawing): [PDF]

Number base pairs (bps)	Expected covarying bps	Observed covarying bps
19	0.4 +/- 0.6	0

DNase hypersensitive sites (95 cell types from ENCODE)	score	cell types
	200	11

Genome Segmentations from ENCODE	GM12878	H1hESC	HeLaS3	HepG2	HUVEC	K562
	R	R	T,R	NULL	R	R

Transcription factor (ChIP)
MYBL2, TEAD4, FOXA1, EP300, SP1, HNF4A, CEBPB, MAFF

RNA binding protein (CLIP)	P-value
NULL

Poly-A selected RNA (Human Body Map 2.0)		Total RNA (Human ENCODE phase 3)
Tissue	Expression level (CPM/RLE)	Tissue	Expression level (CPM/RLE)
Adipose	0	Skin of body	0
Colon	0	Stomach	0
Heart	0	Heart	0.22239
Liver	0	Liver	0
Lung	0	Lung	0.0441702
Ovary	0	Uterus	0.119327
Prostate	0	Urinary bladder	0
Muscle	0	Skeletal muscle	0
Thyroid	0	Thyroid gland	0
Brain	0	Frontal cortex	0
Lymph	0	Temporal lobe	0
Testes	0	Cerebellum	0
Blood	0	Spinal cord	0
Kidney	0	Diencephalon	0
Breast	0	Parietal lobe	0.067479
Adrenalin	0	Occipital	0
		Metanephros	0.157199
		Tongue	0
		Camera type eye	0.0793836

Targeted CRS expression in human fetal brain (CaptureSeq)
Read island identifier	Hybridization temperature	Strand	P-value	Max. Read Count
NULL	NULL	NULL	NULL	NULL

Closest upstream 5' site (CAGE signal)
Distance	Strand	Maximal expression	Aggregated sum of expression	Cell type-specific score
51556	-	68.5625	3177.2900	0.3497

Closest downstream poly-A site (3'-end sequencing)
Distance	Strand	Number of libraries
19181	+	3

Transcript stability (CAGE signal)
Distance	Strand	Expression in control cells	Expression after exosom depletion	Exosome sensitivity
51548	-	1.4375	3.0818	0.5336