Center for non-coding RNA in Technology and Health (RTH)
The center aims at developing technologies, computational methods as well as experimental approaches for analysis of the mammalian genome for non-coding RNAs in relation to (inflammatory) diseases. The center will focus on developing these technologies to exploit them and the findings in relation to diabetes. The center consists of a number of national and international partners, with the core located at the Faculty for Health and Medical Sciences of University of Copenhagen.
The people in the center cover a range of expertises including computational biology, RNA bioinformatics, molecular models in diabetes, RNA biology, animal models, functional genomics and high-throughput sequence analysis.
PhD fellowship in RNA Bioinformatics
Center for non-coding RNA in Technology and Health (RTH), http://rth.dk, Department of Veterinary Clinical and Animal Sciences, Faculty Health and Medical Sciences at University of Copenhagen has an open PhD position in Bioinformatics. We are looking for an enthusiastic person to join our team for three years starting 1 September 2016 or soon thereafter. You will be a hardworking team player and a key person in the project group essential for obtaining successful results.
Transcriptomic landscape of lncRNAs in inflammatory bowel disease
2015-05-13: Researchers lead by Prof Flemming Pociot from RTH publish the first paper on genome-wide transcriptome profiling of human long non-coding RNAs(lncRNAs) and protein-coding genes in Inflammatory bowel disease (IBD). The identified lncRNA transcriptional signature and clinically parameters suggest a biomarker potential in IBD. See the paper here.
For previous news, see here.
Seminar: Genomic selection – status and an outlook to the future
2016-06-27: by Mogens Sandø Lund, Aarhus University. The seminar will take place June 27th, 13.30-14.15 at University of Copenhagen, Grønnegårdsvej 3 ( building 1-61), 2nd floor library, Frederiksberg C.
PhD Defense: Caroline Junker Mentzel
2016-06-28: Porcine Models of Human Obesity - microRNA and Gene Expression. The defence will take place on June 28th, 13:00-16.00 in Fest auditoriet (Aud. A1-01.01), Bülowsvej 17, 1870 Frederiksberg C.
For previous events, see here.
Foldalign 2.5: Parallel version for Foldalign for structural alignment of RNA sequences
The human genome, made up of DNA, consists of three billion building blocks (nucleotides) where some regions (stretches) are complete genes. We all carry variants of the genes and some cause diseases. Here, the goal is to investigate the specific class of genes, the non-coding RNA genes, in relation to diabetes. The non-coding RNA (ncRNA) genes can be the missing components in diseases that previously have been overlooked.
Our research goal is to develop technologies for ncRNA analysis and to search for functional ncRNAs in relation to diabetes and other (inflammatory) diseases.
Foldalign 2.5: multithreaded implementation for pairwise structural RNA alignment
A Systematic Comparison of Purification and Normalization Protocols for Quantitative MicroRNA Expressional Profiling in Insulin-Producing Cells