Center for non-coding RNA in Technology and Health (RTH)
The center aims at developing technologies, computational methods as well as experimental approaches for analysis of the mammalian genome for non-coding RNAs in relation to (inflammatory) diseases. The center will focus on developing these technologies to exploit them and the findings in relation to diabetes. The center consists of a number of national and international partners, with the core located at the LIFE science faculty of University of Copenhagen.
The people in the center cover a range of expertises including computational biology, RNA bioinformatics, molecular models in diabetes, RNA biology, animal models, functional genomics and high-throughput sequence analysis.
Join usWe are always looking for motivated and talented young scientists as well as projects or colaborations within the areas of the center. Feel free to contact us with suggestions or to ask for more information. NewsFellowship to Aashiq Hussain Mirza2012-05-03. RTH PhD student Aashiq Hussain Mirza has been awarded the Poul and Erna Sehested Hansens Foundation Fellowship of 100,000 DKK. PhD Summer Course - apply now
2012-03-02. RTH is co-organizing a PhD course on RNA sequencing and computational analysis together with Centre for Computational and Applied Transcriptomics (COAT). The course is held at Dept. of Biology, University of Copenhagen on August 20-24, 2012. |
EventsSeminar: Circular non-coding RNAs – new type of players in gene regulation.2012-05-23: by Jørgen Kjems, Department of Molecular Biology, Aarhus University on May 23rd at 11.15-12.15 in auditorium A1-01.14, Nordre sti 2, 1st floor, University of Copenhagen, LIFE, Frederiksberg. Seminar: From structural bioinformatics to engineering of new enzymes2012-06-06: by Janusz Bujnicki, Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology, Warsaw, Poland on June 6th at 14.00-15.00 in auditorium A1-01.14, Nordre sti 2, 1st floor, University of Copenhagen, LIFE, Frederiksberg. For previous events, see here. |
Research outsetThe human genome, made up of DNA, consists of three billion building blocks (nucleotides) where some regions (stretches) are complete genes. We all carry variants of the genes and some cause diseases. Here, the goal is to investigate the specific class of genes, the non-coding RNA genes, in relation to diabetes. The non-coding RNA (ncRNA) genes can be the missing components in diseases that previously have been overlooked. Our research goal is to develop technologies for ncRNA analysis and to search for functional ncRNAs in relation to diabetes and other (inflammatory) diseases. Recent publicationsSequence and expression analysis of gaps in human chromosome 20. Experimental identification and analysis of macronuclear non-coding RNAs from the ciliate Tetrahymena thermophila. |
