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Conserved RNA structure in the dark matter

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17way alignment

2017 May 14: RTH researchers discover ~500,000 conserved RNA structures (CRSs) in the dark matter of the genome by using an RNA structural alignment strategy of the vertebrate genomes. The discovered CRSs locate near known genes, regulatory regions and protein binding sites. Expression studies, especially a CRS targeting CaptureSeq experiment in human fetal brain, were employed to characterize the CRSs further. Read the CRS paper here .

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