CRS M2544014

[UCSC Genome browser]   [CRS region C5836021]   [Open all submenus]   [Close all submenus]

+ Summary

Location human (hg38)PscoreFDR
chrX:15594802-15594852 (reverse)64.0711.66 %

[Covariance model (INFERNAL 1.1.1)]


100 species tree

Sequence identityNumber speciesG+C contentAlignment lengthLog Odds SI stem / loop
66.86 %6339.47 %54-0.09
EnergyCompensatory
base pair changes
Mutual informationStructure conservation
SCI
Structure conservation
SECI
-6.65 kcal/mol50.350.240.73

17 species tree

Sequence identityNumber speciesAlignment lengthStructure conservation
SCI
Re-alignment
70.22 %12530.004.05 %

+ Consensus structure

100 species tree

Structure as dot-bracket notation:
((((.(((.....)))))))..................................
Structure as forna illustration (bases are named as consensus sequence and colored by relative entropy):
Color scheme relative entropy

17 species tree

Structure with human sequence and color coding of conservation: [PNG]

+ Alignment

100 species tree

[PNG]  [STOCKHOLM 1.0]


17 species tree

[PNG]  [STOCKHOLM 1.0]

[View 17 species tree alignment]

+ Overlap with RNAcentral

CRS M2544014 is not included in RNAcentral.

+ Annotation

StrandGenomic contextGene identifierDistance (0 if overlap)
ForwardIntergenicantisense|ENSG00000225833|GS1-594A7.38029
ReverseMRNA_Intronmrna_intron|ENSG00000130234|ACE20
BiotypeRfamPhyloCSF
CDSNULLNULL
Repeat MaskerTandem Repeats
NULLNULL
CpG islandExon-Intron Junction
NULL1
Common SNP
(dbSNP 147)
Flagged SNP
(dbSNP 147)
NULLNULL
Disease association from GWAS
NULL

+ Evolutionary selection

+ Covarying base pairs

100 species tree

Consensus structure with covarying base pairs (estimated by R-scape with E-value<0.05) depicted in green (R2R drawing): [PDF]

Number base pairs (bps)Expected covarying bpsObserved covarying bps
70.2 +/- 0.41
Left posRight posScore E-value Substitutions Power
61622.554.9887e-260.03

+ Chromatin signatures

DNase hypersensitive sites (95 cell types from ENCODE)scorecell types
NULLNULL
Genome Segmentations from ENCODEGM12878H1hESCHeLaS3HepG2HUVECK562
CTCFRCTCFCTCFCTCFCTCF

+ Protein binding sites

+ Expression

Poly-A selected RNA (Human Body Map 2.0)Total RNA (Human ENCODE phase 3)
TissueExpression level (CPM/RLE)TissueExpression level (CPM/RLE)
Adipose7.97324Skin of body0
Colon6.22666Stomach0
Heart15.1294Heart1.0592
Liver0.785343Liver0.338545
Lung0Lung0
Ovary0Uterus0.177429
Prostate0.749735Urinary bladder0.146586
Muscle0Skeletal muscle0
Thyroid3.29363Thyroid gland0
Brain0.412773Frontal cortex0
Lymph0.14725Temporal lobe0.0850524
Testes0Cerebellum0
Blood0Spinal cord0
Kidney0Diencephalon0
Breast0Parietal lobe0
Adrenalin0Occipital0
Metanephros0
Tongue0
Camera type eye0.0793836

Targeted CRS expression in human fetal brain (CaptureSeq)
Read island identifierHybridization temperatureStrandP-valueMax. Read Count
NULLNULLNULLNULLNULL

+ Transcript boundaries and stability