Please fill out the submission form and click the Submit button. Input fields marked with a * are required. (Load Example Data)

Multiple Sequence Alignment*
This is the multiple sequence alignment in FASTA format. Either choose a MAF block, an Rfam family, or a customized query by using the text area or uploading a file. [?]
Human (Hg18) 17way MULTIZ alignment: [?] Rfam 10.0 seed alignment: [?]
-
seed no paralogs
or enter alignment:
or upload the alignment file:
  
Phylogenetic Tree
Calculate the score for a given tree in Newick format. [?]
RNA secondary structure
Calculate the score for a given structure in dot-bracket notation. [?]
  
Reliability threshold of evolutionary constrained base pairs [?]
Reliability threshold of evolutionary constrained unpaired bases [?]
Weighting factor for single stranded probabilities (Alpha) [?]
Weighting factor for thermodynamic overlap (Beta) [?]
Maximal percentage of gaps in alignment column [?]
  
E-mail
Job Name
Enter your e-mail adress if you want to receive a notification after the job has finished,
and give your job any custom name.